cocaethylene
Type: Concept
As of November 2026, cocaethylene has been mentioned in one podcast episode on 48 Hours (Nov 2026). A metabolite formed when cocaine and alcohol are combined; its presence and levels were discussed as part of defense theory about cause of death.
Cocaethylene (ethylbenzoylecgonine) is the ethyl ester of benzoylecgonine. It is structurally similar to cocaine, which is the methyl ester of benzoylecgonine. Cocaethylene is formed by the liver in small amounts when cocaine and ethanol coexist in the blood. Cocaethylene was first synthesized in 1885; its side effects were identified in 1989. It acts as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI), with stimulant and euphoriant properties.
| Mentioned in | 1 episode on 1 podcast (as of November 2026) |
|---|---|
| First heard | Nov 2026 on 48 Hours |
| Field | Forensic toxicology / Pharmacology |
Who talks about cocaethylene on podcasts?
cocaethylene came up; the most recent mention was Nov 2026 on 48 Hours.
- Jade Benning's Final Call | Full Episode on 48 Hours (Nov 2026)
What is cocaethylene mentioned alongside?
cocaethylene is most often mentioned alongside fentanyl, Tennessee Titans and Natalie Morales.
Mentioned together: fentanyl, Tennessee Titans, Natalie Morales, Pluto TV, 48 Hours, CBS News, Blaise Taylor, Arkansas State University, Paramount+