Melatonin

Type: Product

As of November 2026, Melatonin has been mentioned in 2 episodes across 1 podcast, first heard Oct 2025 on The Diary Of A CEO. Podcasts mention melatonin primarily as a supplement for sleep regulation. In "Longevity Debate: SHOCKING Weight Loss Truth!" it is recommended for helping with sleep, but caution is advised regarding dosage. In another episode, it is noted that melatonin is a hormone and should not be misused, especially since it interacts with SSRI medications.

Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs. This compound was later identified as a hormone secreted in the brain during the night, playing a crucial role in regulating the sleep-wake cycle, also known as the circadian rhythm, in vertebrates.