dihydrofolate
Type: Concept
As of November 2026, dihydrofolate has been mentioned in one podcast episode on PowerfulJRE (Jun 2024).
Dihydrofolic acid (conjugate base dihydrofolate) (DHF) is a folic acid (vitamin B9) derivative which is converted to tetrahydrofolic acid by dihydrofolate reductase. Since tetrahydrofolate is needed to make both purines and pyrimidines, which are building blocks of DNA and RNA, dihydrofolate reductase is targeted by various drugs to prevent nucleic acid synthesis.
| Mentioned in | 1 episode on 1 podcast (as of November 2026) |
|---|---|
| First heard | Jun 2024 on PowerfulJRE |
Who talks about dihydrofolate on podcasts?
Joe Rogan brought up dihydrofolate; the most recent mention was Jun 2024 on PowerfulJRE.
- Joe Rogan Experience #2060 - Gary Brecka on PowerfulJRE (Jun 2024) — Joe Rogan
What is dihydrofolate mentioned alongside?
dihydrofolate is most often mentioned alongside OCD, 10X Health and folic acid.
Mentioned together: OCD, 10X Health, folic acid, FDA, Food and Drug Administration (FDA), Shopco, Fight or Flight Response, Hypertension, Cold Water Immersion, Growth Hormone