MTHFR

Type: Concept

MTHFR

As of November 2026, MTHFR has been mentioned in 5 episodes across 2 podcasts, first heard Jan 2023 on Gary Brecka. Gary Brecka recommended it: if you have that gene mutation ... simple inability to convert folic acid into the usable form called methylfolate.

Methylenetetrahydrofolate reductase (MTHFR) is the rate-limiting enzyme in the methyl cycle, and it is encoded by the MTHFR gene. Methylenetetrahydrofolate reductase catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a cosubstrate for homocysteine remethylation to methionine. Natural variation in this gene is common in otherwise healthy people. Although some variants have been reported to influence susceptibility to occlusive vascular disease, neural tube def

MTHFR at a glance
Mentioned in5 episodes on 2 podcasts (as of November 2026)
First heardJan 2023 on Gary Brecka
FieldGenetics
DomainGenetics / Epigenetics

What do podcasts say about MTHFR?

3 quotes from Joe Rogan, recorded on Gary Brecka and PowerfulJRE.

  • If you have that gene mutation which 44 of the people in this room have that gene mutation I won't tell you what the nickname is for the MTHFR Gene.
    Gary Brecka · · Hear it
  • Gene mutation called MTHFR.
    Joe Rogan · PowerfulJRE · · Hear it
  • I've had mtrr and the MTHFR.
    Gary Brecka · · Hear it

How do different shows talk about MTHFR?

2 shows discussed MTHFR in these episodes.

Who talks about MTHFR on podcasts?

Joe Rogan brought up MTHFR; the most recent mention was Jun 2024 on PowerfulJRE.

What is MTHFR mentioned alongside?

MTHFR is most often mentioned alongside Methylfolate, trimethylglycine and 5-HTP.

Affiliated with: Methylfolate, trimethylglycine, 5-HTP

Affiliated with: Methylfolate, Thorne, The Journal of Hypertension

Mentioned together: Mother Nature, methionine, hypoxia, B complex, rheumatoid arthritis, red light therapy, photobiomodulation, methylfolate, high blood pressure, alkaline water