Short chain fatty acids
Type: Concept
As of November 2026, Short chain fatty acids has been mentioned in 2 episodes across 1 podcast, first heard Jun 2025 on HUBERMAN LAB. Compounds produced by gut bacteria that influence mitochondrial output, hormone regulation, and inflammation reduction.
Short-chain fatty acids (SCFAs) are fatty acids of two to six carbon atoms. Derived from intestinal microbial fermentation of indigestible foods, SCFAs in human gut are acetic, propionic and butyric acid. Butyrate is the main energy source of colonocytes, making them crucial to gastrointestinal health. SCFAs all possess varying degrees of water solubility, which distinguishes them from longer chain fatty acids that are immiscible.
| Mentioned in | 2 episodes on 1 podcast (as of November 2026) |
|---|---|
| First heard | Jun 2025 on HUBERMAN LAB |
| Field | Biochemistry/Nutrition |
| Domain | Biochemistry |
What do podcasts say about Short chain fatty acids?
2 quotes, recorded on HUBERMAN LAB.
They do this by producing molecules like butyrate and other short chain fatty acids.
HUBERMAN LAB · · Hear itShort-chain fatty acids… can reduce inflammation, protect the brain, and improve mitochondrial efficiency.
HUBERMAN LAB · · Hear it
Who talks about Short chain fatty acids on podcasts?
Short chain fatty acids came up; the most recent mention was Sep 2025 on HUBERMAN LAB.
What is Short chain fatty acids mentioned alongside?
Short chain fatty acids is most often mentioned alongside Jerusalem artichokes, Garlic and Autoag.
Endorsed by: Jerusalem artichokes, Garlic
Affiliated with: Autoag
Affiliated with: Acrimansia muciniphila, Fecalacterium prausnitzii, Bifidobacterium longum
Mentioned together: ATP, Breathwork, Microbiomes, Circadian Rhythm, butyrate, immune system, Cold Exposure, fiber, Neurotransmitter, Serotonin